KULLIYYAH OF PHARMACY

Background

Substance Use Disorder (SUD) is a growing public health problem that occurs worldwide and yet there is still no concrete approach in curbing such predicament. The development of related studies especially on pharmacological interventions seems to be decelerated could be due to the lack of interest from the researchers or profit gained from this population. Patients with SUD are more than always received stigmas and negative perceptions form the community they lived in or even from the healthcare practitioners where this population has been associated with violence, crime, misbehaviour and threat to the community that impede healthcare delivery towards them.

Scope of Research Activities

• Evaluation on the actual burden of SUD disease in our country both for illicit (amphetamine, marijuana, ketum, etc) and prescription drugs.
• Longitudinal evaluation on the outcomes of current treatment approach (patient, community and national level).
• Investigation on the effectiveness of methadone maintenance therapy (MMT) program in this country as one of the harm reduction approaches.
• Identification of possible other treatment approach or strategy in the pipeline to be further developed (eg: PK/PD approach /opioid vaccine).
• Overviewing, proposing and improving current policy regarding SUD.
• Identify the potential drug target to treat poly-drug addiction using pharmacological approach.
• Identify potential compounds in local plants that can be developed to treat drug addiction.

Leader and Members

• Dr Nor Ilyani Mohamed Nazar. (Leader)
  
• Dr Che Suraya Haji Mohd Zin.
• Dr Mohamad Haniki Nik Mohamed.
• Dr Norny Syafinaz Ab Rahman.
• Dr Nor Hidayah Mohd Taufek.
• Dr Irna Elina Ridzwan.
• Mdm Siti Halimah Bux Shaikh Rahman Bux.
• Dr Wael Mohamed Yousef Mohamed (KOM)

Background

Quality Use of Medicines (QUM) refers to the selection of suitable therapeutic interventions followed by assuring the safe and cost-effective use of medicines. The World Health Organization have identified improved patient safety in healthcare as a priority. Pharmacists, in particular, have a key role in ascertaining the quality of medications used for patients, especially in vulnerable populations and patients with chronic diseases. Our research group is more practice-oriented that covers all aspects of quality use of medicines. The current research involves but not limited to the use of medicines in geriatrics and patients with diabetes, cardiovascular diseases, infectious diseases, and psychiatric illness. 

Scope of research activities

1. To assess the quality of use and prescribing of medicines in healthcare settings.
   
2. To describe and assess patterns of medication use and prescribing.
   
3. To investigate the barriers and facilitators towards quality use of medicines.
4. To conduct interventional studies to improve the quality of medication use and prescribing in healthcare settings.
5. To promote and assess the awareness towards medication adherence, medicines information sources and health literacy.
6. To investigate and assess pharmacists’ competencies, education and training that deemed necessary to perform their role in the quality use of medicines.

Leader and members

• Asst. Prof. Dr. Mohamed Hassan Elnaem (Leader)
• Assoc. Prof. Dr. Mohamad Haniki Nik Mohamed
• Asst. Prof. Dr. Muhammad Eid Akkawi
• Asst. Prof. Dr. Abdul Rahman Fata Nahas
• Asst. Prof. Dr. Nor Hidayah Mohd Taufek
• Asst. Prof. Dr. Nor Ilyani Mohamed Nazar
• Asst. Prof. Dr. Norny Syafinaz Ab Rahman
• Asst. Prof. Dr. Siti Hadijah Binti Shamsudin
• Asst. Prof. Dr. Abdulkareem Mohammed Al-Shami
• Asst. Prof. Dr. Tengku Karmila Tengku Kamil

Background

Research methodology is the overall plan ‘that shapes our choice and use of particular methods and links them to the desired outcomes’. Qualitative research is complementary in evaluating the in-depth standpoints and diverse opinions of healthcare practitioners on patient safety, patient advocacy and patient centered care. Qualitative research imparts more flexible meaning, generally emerge from stakeholders’ direct experiences either from their daily lives or professional practices. 

Scope of research activities

1. Rigor in Qualitative Research Instrument
2. Patient- Centered Care through Action Research
3. Patient Safety through Social Phenomenological Approach
4. Cultural Competence in Healthcare through Participatory Action Research
5. Stakeholders Observation on Quality of Life in Patients having Non-communicable Diseases

Leader and members

• Asst. Prof. Dr. Shazia Jamshed (Leader)
• Asst. Prof. Dr. Norny Syafinaz Ab Rahman
  
• Asst. Prof. Dr. Abdul Kareem Mohammed Al Shami
• Assoc. Prof. Dr. Hazrina Hadi
• Asst. Prof. Dr. May Khin Soe 
• Asst. Prof. Dr. Abdul Rahman Fata Nahas

Background

This proposal aims to seek an approval from Kulliyyah of Pharmacy Board ( IIUM ) for establishment of Toxicology research group. Toxicology is an integrated discipline that focuses on effects of xenobiotics to living creatures and environment. The group core strength will be mechanistic toxicology on natural toxins, commonly used herbs and conventional drugs. The group will employ traditional toxicology techniques as well molecular techniques to elucidate mechanism of toxicities. 

Scope of research activities 

i. Isolation and characterization of venom and toxins.

ii. Proteomic study of venom and toxins.

iii. Neurotoxicity and cardiotoxicity studies for venom and toxins.

iv. Nephrotoxicity studies of drug-drug, drug-herbal interactions.

Leader and members

1. Assoc. Prof. Dr. Abdul Razak Kasmuri.
2. Asst. Prof. Dr. Muhamad Rusdi Ahmad Rusmili.
3. Asst. Prof. Dr. Che Anuar Che Muhammad.
4. Asst. Prof. Dr. Rosazra Roslan.
5. Asst. Prof. Dr. Nurul Asyiqin Yusof.
6. Asst. Prof. Dr. Zalikha Ibrahim.

Background

The potential of the domestic pharmaceutical industry has been recognised by the Malaysian government as a strategic industry that should be promoted.  In consistent with this aspiration, the Kulliyyah of Pharmacy, IIUM has designated industrial pharmacy as one of its niche areas to assist in the development of the required human capital and the provision of the relevant new knowledge through research.  One way of promoting high quality research and enhancing good research image of the university is to establish a well-balanced team of researchers through the so-called research clustering.  Hence, the establishment of a research cluster at the Kulliyyah of Pharmacy, which focuses in the area of industrial pharmacy, is the way forward.    

Objectives:

• Form a pool of researchers with diverse expertise enabling complementary researches in pharmaceutical development and production;
• Promote researches addressing emerging problems in pharmaceutical development and production with the ultimate aim of improving quality of life; and
• Provide scientific support to fledging pharmaceutical industries through collaborative research and consultation service.

Leader and Members

• Muhammad Taher (Leader)
• Md. Zaidul Islam Sarker
• Farahidah Mohamed
• Hazrina Abdul Hadi
• A. B. Mohammad Helaluddin
• Juliana Md Jaffri
• Mohd Rushdi Abu Bakar
• Abd Almonem Doolaanea
• Muhamad Salahuddin Haris

Siti Hadijah Shamsuddin

Post Graduate Students in Masters in Pharmaceutical Sciences

• Thazin Win (PhD)
• Rana Samour (PhD)
• Aina Mardiah bt Sabar (MSc)
• Nur ‘Abidah Mohamed Nasir (PhD)
• Shaiqah Mohd Rus (PhD)
• Hamzeh Al Khatib (PhD)
• Md. Abul Kalam Azad (Phd)
• Samah Hamed Abdulrahman Almurisi (Phd)
• Nur Ain Binti Ayob (Phd)
• Alallam Batoul (Msc)
• Luqman Muizzuddin Bin Mohd Rosli (Msc)   

Laboratory(s) and facility(s)
Instrumentation Lab, Advanced Drug Delivery (ADD)S Lab, Dosage Design Lab, Animal Cell Culture, Cosmetic Laboratory
 
Link and Collaboration

• Universitas Muhammadiyah, Jogjakarta
• Universitas Islam Indonesia, Jogjakarta
• Alfaisal University (Riyadh, Saudi Arabia)

Community Services

• Training on Good Manufacturing Practice
• Hand sanitiser preparation and Distribution Covid 19 (2000 bottles) 16-17 March 2020.

Research Grant

• Prototype Research Grant Scheme (PRGS-2019) Production of Hydrogel Sheet Containing Centella asiatica (pegaga) for wound healing.
• Microencapsulation of royal jelly in alginate beads using electrospray: a quality-by-design (QbD) approach. (IRAGS 2018) (RM 20,000)
• Elucidating the anti-cancer Mechanism of thymoquinone nanoparticles involving the MAPK signaling pathway in zebrafish xenografts of colonic and melanoma cancers. in vitro & in vivo study. (FRGS 2017) (RM 88,400)
• Prototype development of process analytical technology (PAT) continuous production line for Nigella sativa oil (NSO)-alginate microparticles. (PRGS 2019) (RM 116,000)
• Reproducible Preparation of Thymoquinone Nanoparticles Using Electrospray. (P-RIGS 2018) (RM 20,000)
• Black Seed Oil Alginate Beads. (Smart Challenge Fund 2018) (RM 871,750)

List of Selected Publications 

• Hassani, A., et al., Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin. Molecules, 2020. 25(9): p. 2244.
•  Azad, A.K., et al., Encapsulation of Black Seed Oil in Alginate Beads as a pH-Sensitive Carrier for Intestine-Targeted Drug Delivery: In Vitro, In Vivo and Ex Vivo Study. Pharmaceutics, 2020. 12(3).
•  Almurisi, S.H., et al., Taste masking of paracetamol encapsulated in chitosan-coated alginate beads. Journal of Drug Delivery Science and Technology, 2020. 56.
•  Mawazi, S.M., et al., Carbamazepine Gel Formulation as a Sustained Release Epilepsy Medication for Pediatric Use. Pharmaceutics, 2019. 11(10): p. 488.     
• Wan Salleh, Wan Mohd Nuzul Hakimi and On, Shamsul and Ahmad, Farediah and Mohd Sirat, Hasnah and Bakhtiar, M. Taher and Sarker, Satyajit Dey and Nahar, Lutfun (2020) A new xanthone and a new benzophenone from the roots of Garcinia hombroniana. Phytochemistry Letters, 35. pp. 216-219
• Ayumi, Rasyidah Ryta and Shaik Mossadeq, Wan Mastura and Zakaria, Zainul Amiruddin and Bakhtiar, M. Taher and Kamarudin, Nadhirah and Hisamuddin, Nadia and Talib, Madihah and Sabar, Aina Mardhiah (2020) Antinociceptive activity of asiaticoside in mouse models of induced nociception. Planta Medica
• Abdul Mudalip, Siti Kholijah and Abu Bakar, Mohd Rushdi and Jamal, Parveen and Adam, Fatmawati (2019) Prediction of mefenamic acid solubility and molecular interaction energies in different classes of organic solvents and water. Industrial & Engineering Chemistry Research, 58 (2). pp. 762-770. ISSN 0888-5885
• Akanda, Md Jahurul Haque and Sarker, Md. Zaidul Islam and Beh, Leykey and Sharifuddin, Md Shaarani and Siddiquee, Shafiquzzaman and Mamat, Hasmadi and Sahena, Ferdosh and Abdul Hamid, Mansoor and Lee, J. S. and Jinap, Selamat(2019) Valuable components of bambangan fruit (Mangifera pajang) and its co-products: a review. Food Research International, 115. 105 -115. ISSN 0963-9969
• Hassan, Syajaratul Jahriah and Adam, Fatmawati and Abu Bakar, Mohd Rushdi and Abdul Mudalip, Siti Kholijah (2019)Evaluation of solvents’ effect on solubility, intermolecular interaction energies and habit of ascorbic acid crystals. Journal of Saudi Chemical Society, 23 (2). pp. 239-248. ISSN 1319-6103
• Jaswir, Irwandi and  Dedi Noviendri and Bakhtiar, Muhammad Taher and Mohamed, Farahidah and Octavianti, Fitri andLestari, Widya and Mukti, Ali Ghufron and Nirwandar, Sapta and Almansori, Bubaker B. Hamad (2019) Optimization and formulation of Fucoxanthin-Loaded Microsphere (F-LM) using Response Surface Methodology (RSM) and analysis of its fucoxanthin release profile. Molecules, 24 (5). pp. 1-16. ISSN 1420-3049
• Syed Hassan, Sharifah Sariah and Adam, Fatmawati and Abu Bakar, Mohd Rushdi and Abdul Mudalip, Siti Kholijah (2019)Evaluation of solvents’ effect on solubility, intermolecular interaction energies and habit of ascorbic acid crystals. Journal of Saudi Chemical Society, 23 (2). pp. 239-248. ISSN 1319-6103
• Ab Ghani, Salinda and Abu Bakar, Noor Fitrah and Abu Bakar, Mohd Rushdi and Yusof, Yus Aniza and Abdul Rahman, Norazah (2018) Granulation of mefenamic acid and poly-ethylene glycol (PEG) using pressure swing granulation (psg) technique in fluidized bed [Pembentukan granul berasaskan asid mefenamik dan polietilena glikol (PEG) menggunakan teknik pengranulan tekanan terayun dalam turus terbendalir]. Malaysian Journal of Analytical Sciences, 22 (2). pp. 318-325. ISSN 1394-2506
• Ab. Hadi, Hazrina and Abdullah, Nurul Shazwani and Ahmed, Qamar Uddin (2018) Exploring the tropical plant wealth: skin and health benefits. In: Current issues in pharmacy. IIUM Press, International Islamic University Malaysia, pp. 149-174. ISBN 9789674184544
• Ab. Hadi, Hazrina and Azillah, Nurul Namira and Ahmed, Qamar Uddin (2018) Microsponge: a potential delivery system for salicylic acid in treating acne. In: Current issues in pharmacy. IIUM Press, International Islamic University Malaysia, pp. 127-148. ISBN 9789674184544
• Ab. Hadi, Hazrina and Azman, Amirah (2018) A step forward to develop pharmacist with cosmeceutical knowledge in community pharmacy setting: a pilot study. In: 4th International Pharmaceutical Research Conference 2018, 25th-26th August 2018, Cyberjaya, Malaysia. (Unpublished)
• Ab. Hadi, Hazrina and Razak, Luqman (2018) Effects of smoking on skin conditions: in vivo assessment. In: 4th International Pharmaceutical Research Conference 2018, 25th-26th August 2018, Cyberjaya, Malaysia. (Unpublished)
• Ab. Hadi, Hazrina and Zamery, Muhammad 'Izzuddin and Zaiter, Ahmad (2018) Cosmeceutical applications of clay minerals: a review. In: Current issues in pharmacy. IIUM Press, International Islamic University Malaysia, pp. 275-296. ISBN 9789674184544
• Abdul Kalam, Azad and Doolaanea, Abd Almonem and Al-Mahmood, Sinan Mohammed Abdullah and Wan Sulaiman, Wan Azizi and Al-Ani, Imad Matloub Dally (2018) Microencapsulation of peppermint oil using an ionic gelation electrospray technique. In: 4th International Pharmaceutical Research Conference 2018, 25th-26th August 2018, Cyberjaya, Malaysia. (Unpublished)
• Abdul Latif, Nurul Hazwani and Bakhtiar, M. Taher and Md Jaffri, Juliana and Amri, Mohamad Shahreen and Abdul Kudos, Muhammad Badri and Wan Sulaiman, Wan Mohd Azizi and Darnis, Deny Susanti (2018) Selected natural agents used for cholesterol controls. Nutrition & Food Science, 48 (2). pp. 301-317. ISSN 0034-6659
• Abdul Mudalip, Siti Kholijah and Abu Bakar, Mohd Rushdi and Jamal, Parveen and Adam, Fatmawati and Che Man, Rohaida and Sulaiman, Siti Zubaidah and Mohd Arshad, Zatul Iffah and Md. Shaarani, Shalyda (2018) Effects of solvents on polymorphism and shape of mefenamic acid crystals. In: Malaysia Technical Universities Conference on Engineering and Technology (MUCET 2017)., 6-7 Dec,2017, Penang.

Background

Big data in healthcare refers to electronic health data sets that are so large and
complex that it would be difficult to manage and analyze using traditional
software and data management tools and methods. Big data in healthcare is also
known as large health care databases which is one of the sources for drug
utilization study. It is often used to address research questions on drug use and
drug effect such as evaluation of the processes of prescribing, dispensing and
consumption of medicines to improve the quality use of medicines in populations.
Large healthcare databases, which contain data collected during routinely
delivered healthcare to patients, can serve as a valuable resource for generating
actionable evidence to assist in medical and healthcare policy decision-making.
The sources of large healthcare data include electronic medical records, health
insurance claims and patient registries. Data may be collected on drug sales,
prescriptions, drug distribution chain, pharmaceutical and medical billing. The
scope of the databases may be international, national or local. The databases
may be diagnosis-linked or non-diagnosis-linked. Diagnosis-linked data enable
drug use to be analyzed according to patient characteristics, therapeutic groups,
diseases or conditions and, in the best of cases, clinical outcome. A useful
analysis requires an understanding of the sources and organization of the data.
Harnessing the power of information contained in large healthcare databases,
while paying close attention to their inherent limitations, is critical to generate
rigorous evidence-base for medical decision-making and ultimately enhancing
patient care.

Scope of Research Activities

1. To assess the quality of use and prescribing of medicines in healthcare settings.
   
2. To describe and assess patterns of medication use and prescribing.
   
3. To investigate the barriers and facilitators towards quality use of medicines.
4. To conduct interventional studies to improve the quality of medication use and prescribing in healthcare settings.
5. To promote and assess the awareness towards medication adherence, medicines information sources and health literacy.
6. To investigate and assess pharmacists’ competencies, education and training that deemed necessary to perform their role in the quality use of medicines.

Leader and Members

• Asst. Prof. Dr. Mohamed Hassan Elnaem (Leader)
• Assoc. Prof. Dr. Mohamad Haniki Nik Mohamed
• Asst. Prof. Dr. Muhammad Eid Akkawi
• Asst. Prof. Dr. Abdul Rahman Fata Nahas
• Asst. Prof. Dr. Nor Hidayah Mohd Taufek
• Asst. Prof. Dr. Nor Ilyani Mohamed Nazar
• Asst. Prof. Dr. Norny Syafinaz Ab Rahman
• Asst. Prof. Dr. Siti Hadijah Binti Shamsudin
• Asst. Prof. Dr. Abdulkareem Mohammed Al-Shami
• Asst. Prof. Dr. Tengku Karmila Tengku Kamil

Post graduate students

Open for recruitment

Laboratory(s) and Facility(s) 

• Pharmacy practice laboratory and discussion room

Link and Collaboration

• Department of Pharmacy, IIUMMC.
• Department of Internal Medicine, Kulliyyah of Medicine, IIUM.
• Department of Family Medicine, Kulliyyah of Medicine, IIUM.
• AP. Dr. Hasniza Zaman Huri, Department of Pharmacy, University of Malaya
• Dr. Noordin Othman, QUMPRG, Department of Clinical and Hospital Pharmacy, Taibah University, Saudi Arabia.

Community Services

• Conduct home-medication review (HMR) for elderly patients Campaign to improve health literacy among the public focusing on cardiovascular disease prevention, diabetes and mental health.

Research Grant

• Evaluation of the factors associated with lipid-lowering therapy use among patients with type 2 diabetes mellitus and the impact of academic detailing, 20,000 (2017): In Progress
• Evaluation of lipid-lowering therapy use among patients with type 2 diabetes mellitus in Pahang, 20,000 (2016): completed. 
• Development and Assessment of a Smartphone Application to Help Healthcare Providers Avoid Potentially Inappropriate Prescribing among Hospitalized Elderly Patients, 20,000 (2015): completed.

List of Selected Publications

• Elnaem MH, Nik Mohamed MH, Zaman Huri H, Azarisman SM. Effectiveness and prescription pattern of lipid-lowering therapy and its associated factors among patients with type 2 diabetes mellitus in Malaysian primary care settings. Ther Clin Risk Manag. 2019; 18: 137–145.
• Akkawi ME, Nik Mohamed MH, Md Aris MA, Does inappropriate prescribing affect elderly patients’ quality of life? a study from a Malaysian tertiary hospital. Qual Life Res. 2019.
• Akkawi ME, Nik Mohamed MH, Are physicians and clinical pharmacists aware and knowledgeable enough about inappropriate prescribing for elderly patients? Findings from Malaysia. Eur J Hosp Pharm. 2018; 25, e29-e34.
• Elnaem MH, Nik Mohamed MH, Zaman Huri H, Azarisman SM. Impact of educational outreach intervention on enhancing health care providers’ knowledge about statin therapy prescribing in Malaysian patients with type 2 diabetes mellitus. J Eval Clin Pract. 2018; 24: 521–527.
• Akkawi ME, Nik Mohamed MH, Influence of hospitalization on potentially inappropriate prescribing among elderly patients in a Malaysian community. Trop J Pharm Res. 2018; 17(1):151-160.
• Elnaem MMH, Nik Mohamed MMH, Huri HZ, Azarisman SM. Patterns of statin therapy prescribing among hospitalized patients with Type 2 diabetes mellitus in two Malaysian tertiary hospitals. Trop J Pharm Res. 2017; 16: 3005–3011. 
• Elnaem M, Nik Mohamed M, Huri HZ, Azarisman SM, Elkalmi RM. Statin therapy prescribing for patients with type 2 diabetes mellitus: A review of current evidence and challenges. J Pharm Bioallied Sci. 2017; 9: 80.

To be Updated

Background

DRG is a focal point for all groups interested in skin biology and the delivery of actives in skin. DRG we will be conducting studies on topical and transdermal compound delivery, skin biology and skin tissue engineering for pharmaceutical and cosmeceutical applications. The group not only will use chemicals as active ingredients in the formulations, but also will do extraction to isolate and characterised potential bioactive compounds for skin applications. The bioactive compounds will also undergo metabolite profiling in order to identify the responsible compounds for its pharmaceutical and/or cosmeceutical activities. Different biophysical techniques will be used to probe the mechanisms of skin penetration and modulation of the active ingredients. Cutting edge technologies and delivery systems such as microspheres, nanosponges, hydrogel will be used to ensure the actives can exert their activities to the target sites. Our current performance is indicated as follows.

Scope of Research Activities

1. Isolation, characterisation and metabolite profiling of bioactive compounds with potential dermatology applications
2. Rational design of formulations for skin formulations
3. Probing the action of penetration modulating agents 
4. Optimisation and characterization of the formulations 
5. Elucidating the activities of the bioactive and/or skin formulations in in-vitro 
6. Assessment of the formulation efficacy in animal models 
7. Pre-clinical studies of skin formulations 
8. Scale up of the formulations

Leader and Members

• Assoc. Prof. Dr. Hazrina Ab Hadi (Leader - Kulliyyah of Pharmacy) 
• Prof. Zaidul Sarker (Kulliyyah of Pharmacy)
• Assoc. Prof. Dr. Alfi Khatib (Kulliyyah of Pharmacy) 
• Assoc. Prof. Dr. Norazian bt Mohd Hasan (Kulliyyah of Pharmacy)
• Assoc. Prof. Dr. Abdul Razak Kasmuri (Kulliyyah of Pharmacy)
• Asst. Prof. Dr Abd Monem Doolaanea (Kulliyyah of Pharmacy)
• Asst. Prof. Dr. Mohd Azri Abd Jalil (Kulliyyah of Nursing)

Post Graduate Students (as Main Supervisor)

a. On-going (as main supervisor or chairman)

i. Ph.D students:

• Noor Shimariza Ashikin Binti Wan Hussin (G1820970). Thesis title: Development of resiquimod loaded nanosponges based topical gel formulation for actinic keratosis treatment. Supervisor: Assoc. Prof. Dr. Hazrina Ab Hadi
• Sharifah Shakirah Binti Syed Omar (G1921638). Thesis title: Fabrication of nanosponges for topical delivery of retinoic acid for skin acne. Supervisor: Assoc. Prof. Dr. Hazrina Ab Hadi.
• Nipun Tanzina Sharmin (G1710044). Thesis title: Evaluation of anti-diabetic activity of Psychotria malayana Jack leaves and characterization of its bioactive compounds using metabolomics and molecular docking simulation. Supervisor: Assoc. Prof. Dr. Alfi Khatib.
• Md. Abdur Rashid Mia (G1817363): Thesis title: Simultanious extraction and fractionation of essential oils from cinnamon using various techniques of supercritical fluid. Supervisor: Prof. Zaidul Sarker
• Tariqul Islam (G1918364). Thesis title: Amide coupling interaction for elimination organic solvent from generic pharmaceuticals with supercritical fluid. Supervisor: Prof. Zaidul Sarker
• Siti Zaleha Binti Raduan (G1828348). Thesis title: The neuroprotective effects of litsea garciae bark extract in zebra fish Alzhemier’s model. Supervisor: Assoc. Prof. Dr Abdul Razak Kasmuri
• Alkhatib Hamzeh (G1822885). Thesis title: Optimization and stability evaluation of pilot scale black seed oil alginate beads formulation. Supervisor: Asst. Prof. Dr Abd Monem
• Md. Abul Kalam Azad (G1629991). Thesis title: Synergic effect of peppermint oil and black seed oil in an animal model of irritable bowel syndrome: Formulation and Efficacy Evaluation. Supervisor: Asst. Prof. Dr Abd Monem
• Nur Ain Binti Ayob (G1614796). Thesis title: Gene therapy of colon cancer using SIRNA encapsulated in nanoparticles. Supervisor: Asst. Prof. Dr Abd Monem
• Nur `Abidah Binti Mohamed Nasir (G1828104). Thesis title: Process analytical technology based approaches for continuous manufacturing of nigella sativa oil-alginate microparticles (NSO-Alg MPs). Supervisor: Asst. Prof. Dr Abd Monem
• Shaiqah Binti Mohd Rus (G1822486). Thesis title: Development and validation of electrospray manufacturing process for black seed oil alginate beads. Supervisor: Asst. Prof. Dr Abd Monem

• ii. Master students:

• Mohammad Ghazali Bin Ab Salam (G1636467). Thesis title: Prevalence of microbial contamination study of cosmetic products in Malaysia. Supervisor: Assoc. Prof. Dr. Hazrina Ab Hadi.
• Alallam Batoul (G1816334). Thesis title: Gene editing using crispr plasmid DNA loaded alginate nanoparticles. Supervisor: Asst. Prof. Dr Abd Monem.
• Luqman Muizzuddin Bin Mohd Rosli (G1610697). Thesis title: The formulation of thymoquinone- loaded PLGA nanoparticles and cytotoxicity in malignant melanoma A375 cell lines in vitro. Supervisor: Asst. Prof. Dr Abd Monem.

b. Graduated (as main supervisor or chairman)

i. Ph.D – no.of students:

• Assoc. Prof. Dr. Hazrina -1
• Prof. Zaidul Sarker – 7 
•  Assoc. Prof. Dr. Alfi Khatib - 2 
• Assoc. Prof. Dr. Abdul Razak Kasmuri - 3 
• Asst. Prof. Dr Abd Monem - 1

ii. Master – no.of students:

• Assoc. Prof. Dr. Hazrina - 7
• Prof. Zaidul Sarker – 2 
• Assoc. Prof. Dr. Abdul Razak Kasmuri - 3 
• Asst. Prof. Dr Abd Monem - 3 
• Assoc. Prof. Dr. Alfi Khatib - 2 
• Assoc. Prof. Dr. Norazian Mohd Hasan - 4

Laboratories and Facilities

a. Laboratories: Pharmacokinetics Lab, Dosage Design Lab, Advanced Drug Delivery Lab, Analytical Chemistry Research Lab 2, Tissue Culture Lab, Herbal Lab. 

b. Facilities: Franz diffusion cells set-up, Dermalab Combo, Freeze dryer, FTIR, Analytical and Preparative HPLC, UV-Vis

Link and Collaboration

• MOA with Hannan Medispa Sdn Bhd

Community Services 

• Education on using natural products in daily skin care routine
• Education on using safe cosmetic products to avoid adverse effect

Target group : IIUM communities

Research Grant (as PI-on going)

• FRGS19-092-0701. Probing the cellular and molecular mechanisms of skin barrier repair in atopic dermatitis by Benincasa hispida seed extract. Amount: RM 180,800 PI: Assoc. Prof. Dr. Hazrina Hadi
• SPP20-009-0009. Fabrication of Nanosponges for Topical Retinoic Acid Delivery for Skin Acne - Phase 1. Amount: RM 50,015. PI: Assoc. Prof. Dr. Hazrina Hadi 
• FRGS19-002-0610: Research title: Mechanism of amide coupling interaction for eliminating organic solvent from generic pharmaceuticals with supercritical CO2 Amount: RM 123,000. PI: Prof Zaidul Sarker 
• P-RIGS18-027-0027. Identification of alpha-glucosidase inhibitors from P. malayana leaf extract using liquid chomatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking. Amount: RM 20,000. PI: Assoc. Prof. Dr. Alfi Khatib. 
• PRGS19-005-0571. Prototype development of process analytical technology (PAT) continuous production line for Nigella sativa oil (NSO)-alginate microparticles. Amount: RM 116,000 . PI: Asst. Prof. Dr Abd Monem 
• SMF18-001-0001. Black Seed Oil Alginate Beads. Amount: RM 976,750. PI: Asst. Prof. Dr Abd Monem 
• FRGS17-005-0571. Elucidating the anti-cancer mechanism of thymoquinone nanoparticles involving the MAPK signaling pathway in zebrafish xenografts of colonic and melanoma cancers. in vitro & in vivo study. Amount: 93,704.00. PI: Asst. Prof. Dr Abd Monem

List of Selected Publications (1 selected publication for 1 lecturer)

• Hadi, H., Awadh, A. I., Zamli, M., Ai, N. A., & Jamshed, S. (2020). Insight of Malaysian Users of Cosmetic Regarding Cosmetovigilance. Cosmetics, 7(2), 45.
• Razali, M., Zainal, Z., Maulidiani, M., Shaari, K., Zamri, Z., Idrus, M. M., Khatib, A., Abas, F., Ling, Y., Rui, L., Ismail, I. S.Classification of raw stingless bee honeys by bee species origins using the NMR-and LC-MS-based metabolomics approach. Molecules, 23 (9), 1-18 (2018)
• Norazian Mohd Hassan, Nurul Asyiqin Yusof, Amirah Fareeza Yahaya, Nurul Nasyitah Mohd Rozali, Rashidi Othman (2019). Carotenoids of Capsicum fruits: pigment profile and health-promoting functional-attributes. Antioxidants, 8 (10). , 0 pp. 1-25. ISSN 2076-3921
• Mohd Azri Abdul Jalil, Abdul Razak Kasmuri, Hazrina Ab. Hadi (2017). The evaluation of physicochemical and anti-microbial properties of honey based hydrogel. Proceedings of the Malaysia Pharmaceutical Society Conference 2017 Malaysian Journal of Pharmacy, 3 (1 (Supplement)). , 0 pp. 25-25. ISSN 1675-3666
• Mohd Azri Abdul Jalil, Abdul Razak Kasmuri, Hazrina Ab. Hadi (2017). Stingless bee honey, the natural wound healer: a review.   Skin Pharmacology and Physiology, 30. , 0 pp. 66-75. ISSN 1660-5527
• Sukmasari, S., O. A. J. A. Qader, M. N. A. Rahman, M. Ibrahim and A. A. Doolaanea (2018). The release profiles of baccaurea angulata extract from various gelling agents. Journal of Pharmaceutical Sciences and Research 10(1): 45-50.