Staff Directory


Azzmer Azzar Bin Abdul Hamid

Academic Qualification

  • Doctor of Phisolophy (Biotechnology) - Doctor of Philosophy, International Islamic University Malaysia

Azzmer Azzar Bin Abdul Hamid (Assoc. Prof. Dr.)

Associate Professor
IIUM Kuantan Campus

KULLIYYAH OF SCIENCE


azzmer@iium.edu.my
5036


Expert Profile



Azzmer Azzar bin Abdul Hamid obtained his Ph.D. in Biotechnology from IIUM and subsequently reported duty as a lecturer at the Department of Biotechnology within the Kuliyyah of Science at the IIUM Kuantan Campus. His professional journey commenced with a position as a tutor at Open University Malaysia in Johor Bahru, where he instructed Biology courses encompassing Eukaryotic Diversity, Basic Genetics, Current Issues in Science, and Plant Physiology. Within the realm of Research and Development (R&D), he amassed valuable experiences by serving as a research assistant and later as a research officer at the Faculty of Bioscience and Medical Engineering at UTM in Johor. At present, Dr. Azzmer holds the title of Associate Professor at the Department of Biotechnology in the Kulliyyah of Science at the International Islamic University Malaysia (IIUM) Kuantan Campus. His primary research focus revolves around molecular modeling of environmental and disease proteins.

Dr. Azzmer secured research funding, acting as the principal researcher for an internal grant known as RMCSDG and as the Principal Investigator for a fundamental research scheme grant (FRGS). His contributions to the field are evident through the publication of articles in highly reputable journals, covering topics such as protein modeling, rational design, molecular biology, and enzyme kinetics. Beyond his research endeavors, he has dedicated his expertise to the Ministry of Education, serving as an examiner for the Matriculation program and as a reviewer for scientific journals such as the Journal of Biomolecular Structure & Dynamics. On a national level, he has been appointed as an executive committee member for the Malaysian Society of Bioinformatics & Computational Biology (MasBIC).


Area of Specialisation


  • Biotechnology ~ Biotechnology ~ Industrial and Environmental Biotechnology ~ Enzyme Technology - Molecular Cloning, Protein Expression, Molecular Docking, Molecular Dynamics Simulation


Professional Membership


  • 2019 - 2022: Member of Profesional Body / Association: (Exco), Malaysian Society of Bioinformatics & Computational Biology (MasBIC)


Teaching Responsibilities


BIOINFOMATICS 2020/2021 2018/2019 2017/2018 2016/2017 2015/2016 2014/2015
BIOINFORMATICS 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020
BIOREMEDIATION 2023/2024 2022/2023 2021/2022 2019/2020 2018/2019 2016/2017
ENVIRONMENTAL BIOTECHNOLOGY 2023/2024 2022/2023 2021/2022 2020/2021 2019/2020 2018/2019 2017/2018 2016/2017 2015/2016
ENVIRONMENTAL TOXICOLOGY/ POLLUTION 2020/2021
FINAL YEAR PROJECT 2020/2021 2014/2015
FINAL YEAR PROJECT II 2020/2021
INTEGRATED WASTE MANAGEMENT 2023/2024 2022/2023 2021/2022
INTRODUCTION TO BIOINFORMATICS 2015/2016 2014/2015
PROTEIN BIOTECHNOLOGY 2017/2018 2016/2017 2015/2016
WASTE MANAGEMENT AND USAGE 2020/2021 2019/2020 2018/2019 2017/2018


Supervision


Characterization Of Betanodavirus And The Identification Of Antigenic Determinants Of The Capsid Protein For Development Of A Recombinant Protein Vaccine.
Ph.D Completed 2022 Co-supervisor
Industrial Influence On Balok And Tunggak River Inferred Through Environmental Technique And Edna Metabarcoding.
Ph.D In Progress Main Supervisor
Elucidating The Prophylactic Potential Of Kelulut Honey (Kh) In Modulating Angiotensin-Converting Enzyme 2 (Ace-2) As Covid-19 Target Enzyme.
Ph.D In Progress Co-supervisor
Novel In Silico Selex In Designing Aptamer Hairpin For In Vitro Detection Of He4: An Ovarian Cancer Biomarker.
Ph.D In Progress Co-supervisor
Effectiveness Of Newly Developed Aptamer-Based Rapid Detection Kit Detecting Streptococcus Agalactiae In Greochromis Spp..
Ph.D In Progress Co-supervisor
Rhamnolipid Production By Biosurfactant- Producing Bacteria During Hydrocarbon Biodegradation And Their Interaction With Ndo-Pah Complexes.
Master Completed 2023 Co-supervisor
In Silico Structural Interactions Of Trichoderma Harzianum T12 Β-Glucosidase Towards The Cell Wall Components Of Macrophomina Phaseolina.
Master Completed 2021 Main Supervisor
Identification Of Potential Inhibitors Of Human Hexokinase Ii For The Development Of Anti-Dengue Therapeutics.
Master Completed 2021 Co-supervisor
Molecular Characterization Of Channel Catfish Virus (Ccv) Isolated From Cage-Cultured Pangasius Hypophthalmus Farmed In Pahang River, Malaysia.
Master Completed 2020 Co-supervisor
Fundamental Study Of The Structure Glycerol- 3- Phosphate Acyltransferase (Gpat) Protein From Chlorella Sp. On Understanding Of Lipid Synthesis.
Master Completed 2020 Co-supervisor
The Mechanistic Role Of Active Site Residues In Non-Stereospecific Haloacid Dehalogenase E (Dehe) Using Computational Approach .
Master Completed 2019 Main Supervisor
Bacterial Community Of Marine Sponges From Pulau Bidong And Pulau Karah, Terengganu And The Haloacid Degrading Potential.
Master Completed 2019 Main Supervisor
Molecular Docking And Molecular Dynamics Study On Potential Ebola Matrix Protein Vp40 Inhibitors.
Master Completed 2019 Co-supervisor
Molecular Binding Affinity Between Mutated Furin Cleavage Site (Fcs) Of Sars-Cov -2 Spike And Host Furin Protease: A Multi-Scale Simulation Study.
Master In Progress Main Supervisor
Structural And Functional Studies Of Kaurene Synthase In Stevia Rebaudiana Ms007 Via In Silico Approach.
Master In Progress Co-supervisor


Research Projects


Completed
2022 - 2023 Sci-ON
2020 - 2022 PEMELIHARAAN DAN PEMULIHARAAN TASIK DI KOMPLEKS YAYASAN PAHANG DAN KAWASAN SEKITAR
2019 - 2023 The mechanism of action of EPS from G. lucidem as ?-glucosidase inhibitors and to identify its role in the regulation of blood glucose level
2018 - 2022 Quest on Finding Potential Ebola VP40 Inhibitors: Molecular Dockings and Molecular Dynamics Simulation Studies
2017 - 2021 In silico Study of Selected Flavonoids from Nelumbo nucifera as Potential Pancreatic Lipase Inhibitor
2017 - 2021 Phytomining of gold from mine wastes by Jatropha Curcas
2017 - 2020 Computational investigation on the interaction of ?-Glucosidase with the cell wall component of pathogenic fungus, Macrophomina phaseolina
2015 - 2019 Fundamental Study of the Structure of the Glycerol-3-Phosphate Acyltransferase (GPAT) Protein from Chlorella Sp. on Understanding the Mechanism of Lipid Synthesis
2015 - 2016 An Assessment on Microbial Contamination in Drinking Water Wells Exposed to Different Degrees of Submergence during Flood
2015 - 2019 The Mechanistic Role of Active Site Residues in Non-Stereospecific Haloacid Dehalogenase E (Dehe) Using Computational Approach
2014 - 2018 Identification of 3CP-Degrading Bacteria from Marine Sponge and its ?-dehalogenase Gene
On-Going
2024 - Present Complete Genome Analysis of an Aquaculture Fish Pathogen Serotype III Streptococcus Agalactiae
2024 - Present Effectiveness of Newly Developed Aptamer-Based Rapid Detection Kit Detecting Streptococcus Agalactiae in Oreochromis SPP in Different Water Body
2024 - Present MOLECULAR CHARACTERIZATION OF ISOLATED EDWARDSIELLA ICTALURI FROM CAGED-CULTURED PANGASIUS HYPOPHTHALMUS IN PAHANG RIVER
2023 - Present Unravelling Microbial Communities in the Rhizosphere of Dipterocarpaceae through Metagenomic approach
2023 - Present Antiviral Drugs for Viral Nervous Necrosis (VNN) in Marine
2023 - Present Effectiveness of Newly Developed Rapid Detection Kit Detecting Streptococcus Agalactiae in Oreochromis SPP in Different Water Body
2022 - Present Elucidating the prophylactic potential of Kelulut honey in modulating angiotensin-converting enzyme 2 (ACE2) as COVID-19 target enzyme
2022 - Present Metagenomics Analysis of Bacterial Communities and Their Functional Profiles in Water and Sediments of The Pahang River
2021 - Present The Optimisation, Assembly, Testing, Validation, and Scaling Up of the Nanotech COVID19 Rapid Test Kit - Protein Modelling / Kinetics and Rational Design
2020 - Present Structure-based Virtual Interactions of SARS-CoV-2 Spike protein for Molecular Diagnostic & Drug Repurposing
2019 - Present Investigation on production of biosurfactants and their effect on the molecular interactions of polycyclic aromatic hydrocarbons with ring hydroxylating dioxygenase during biodegradation
2017 - Present Development of Effective Microbes for Decomposition Process


Publications


Article

2024 An ensemble docking-based virtual screening and molecular dynamics simulation of phytochemical compounds from Malaysian Kelulut Honey (KH) against SARS-CoV-2 target enzyme, human angiotensin-converting enzyme 2 (ACE-2). Journal of Biomolecular Structure and Dynamics, () pp. 1-30
2024 Baseline amplicon sequencing data for the ITS2 region in the green honey of Banggi Island, Sabah. Data in Brief, 52 (1) pp. 1-8
2024 Green honey of Banggi Island: a preliminary anti-diabetic study on zebrafish model. Heliyon, 10 (4) pp. 1-8
2023 Interaction of the nanobio-based reagent with sodium fluorescein and lipids via bioinformatics for forensic fingerprint visualisations. Journal of Biomolecular Structure and Dynamics, () pp.
2023 LC-MS/MS-QTOF dataset of compounds detected in kelulut honey of the stingless bees, Heterotrigona itama and Tetrigona binghami from Kuantan, Pahang, Malaysia. Data in Brief, 49 (August 2023) pp. 1-8
2023 Molecular modelling and dynamics of Kaurene Synthase involved in Stevia Rebaudiana (Accession MS007) Terpene Biosynthesis. Asia Pacific Journal of Molecular Biology and Biotechnology (APJMBB), 31 ((2) suppl.) pp. 82-82
2023 The first ITS2 sequence data set of eDNA from honey of Malaysian giant honeybees (Apis dorsata) and stingless bees (Heterotrigona itama) reveals plant species diversity. BMC Research Notes, 16 () pp. 1-4
2022 Angiotensin Converting Enzyme (ACE) inhibitionactivity by Syzygium polyanthum Wight (Walp.) leaves: mechanism and specificity. Pharmacognosy Journal, 14 (1) pp. 763-84
2022 Molecular interactions of trichoderma β-1,4-glucosidase (ThBglT12) with mycelial cell wall components of phytopathogenic Macrophomina phaseolina. Journal of Biomolecular Structure and Dynamics, () pp. 1-17
2022 P-glycoprotein: new insights into structure, physiological function, regulation and alterations in disease. Heliyon, 8 (6) pp. 1-12
2021 COVID19: bahaya varian Delta dan bagaimana ia menakluki dunia. Majalah Sains, 12 Aug 2021 () pp.
2021 Genomic analysis of a functional haloacid-degrading gene of Bacillus megaterium strain BHS1 isolated from Blue Lake (Mavi Gölü, Turkey). Annals of Microbiology, 71 (1) pp. 1-12
2021 In Silico Docking of Epicatechin, Corilagin and Quercetin as Potential Pancreatic Lipase Inhibitor for obesity treatment. International Journal of Allied Health Sciences, 5 (2) pp. 2194-2220
2021 LCMS dataset on compounds in syzygium polyanthum (wight) walp. leaves variant from the East coast of Peninsular Malaysia. Data in Brief, 39 () pp.
2021 Molecular docking analysis of designed ligands on VP40 of Ebola Virus. Malaysian Journal of Chemistry, 23 (2) pp. 63-73
2021 Phytoremediation of Arsenic in Mine Wastes by Acacia mangium. Remediation, 2021 () pp. 1-11
2021 Virtual screening for potential inhibitors of human hexokinase II for the development of anti-dengue therapeutics. BioTech, 10 (1) pp. 1-28
2020 Characterisation and computational analysis of a novel lipase nanobio-based reagent for visualising latent fingerprints on water-immersed glass slides. Process Biochemistry, 96 () pp. 102-112
2020 Characterization of a 2,2-dichloropropionic acid (2,2-dcp) degrading alkalotorelant bacillus megaterium strain bhs1 isolated from Blue Lake in Turkey. Journal of Tropical Life Science, 10 (3) pp. 245-252
2020 Comparative modelling studies of fruit bromelain using molecular dynamics simulation. Journal of Molecular Modeling, 26 (6) pp.
2020 Computational quest for finding potential Ebola VP40 inhibitors: a molecular docking study = [pencarian pengiraan untuk mencari potensi perencat Ebola VP40: suatu kajian mengedok molekul]. Sains Malaysiana, 49 (3) pp. 537-544
2020 Environmental forensic study: tracing of pollution sources using environmetric technique in Balok and Tunggak Rivers near Gebeng industrial area, Kuantan, Pahang, Malaysia. Desalination and Water Treatment, 191 () pp. 118-125
2020 Functional profiling of bacterial communities in Lake Tuz using 16S rRNA gene sequences. Biotechnology & Biotechnological Equipment, 35 (1) pp. 1-10
2020 Functional profiling of bacterial communities in Lake Tuz using 16S rRNA gene sequences. Biotechnology and Biotechnological Equipment, 35 (1) pp. 1-10
2020 Identification and characterization of a 2, 2-dichloropropionic acid (2, 2-DCP) degrading alkalotorelant bacterium strain BHS1 isolated from Blue Lake, Turkey. Journal of Tropical Life Science, 10 (3) pp. 245-252
2020 In silico mutation on a mutant lipase from Acinetobacter haemolyticus towards enhancing alkaline stability. Journal of Biomolecular Structure and Dynamics, 38 (15) pp. 4493-4507
2020 Molecular docking and dynamic simulation of astragalin reveals inhibitory potential against pancreatic lipase. International Journal of Allied Health Sciences (IJAHS), 4 (2) pp. 1175-1190
2020 Molecular docking and molecular dynamics simulations studies on β-glucosidase and xylanase Trichoderma asperellum to predict degradation order of cellulosic components in oil palm leaves for nanocellulose preparation. Journal of Molecular Structure and Dynamics, () pp. 1-14
2020 The assessment of three dimensional modelling design for single strand DNA aptamers for computational chemistry application. Biophysical Chemistry, 267 () pp.
2019 Functional annotation of selected streptococcus pneumoniae hypothetical proteins. Malaysia Journal of Science Health and Technology, 4 (Special Issue, KoSiST 2018) pp. 12-16
2019 In silico screening of aptamers configuration against hepatitis B surface antigen. Advances in Bioinformatics, 2019 (12 pages) pp. 1-12
2019 In silico structural and functional annotation of nine essential hypothetical proteins from Streptococcus pneumoniae. Indonesian Journal of Chemistry, () pp.
2019 Microbial hydrolytic enzymes: In silico studies between polar and tropical regions. Polar Science, 20 (part 1) pp. 9-18
2019 The mechanistic role of active site residues in non-stereo haloacid dehalogenase E(DehE). Journal of Molecular Graphics and Modelling, 90 () pp. 219-225
2018 Comparative structural analysis of fruit and stem bromelain from Ananas comosus. Food Chemistry, 566 () pp. 183-191
2018 Effect of 2014 massive flood on well water qualities: a case study on Kelantan River basin, Malaysia. Journal of Water and Land Development, 2018 (38) pp. 127-136
2018 In silico study of carvone derivatives as potential neuraminidase inhibitors. Journal of Molecular Modeling, 24 (4) pp. 1-13
2018 Interaction of monomeric Ebola VP40 protein with a plasma membrane: a coarse-grained molecular dynamics (CGMD) simulation study. Journal of Molecular Graphics and Modeling, 82 () pp. 137-144
2018 Molecular docking analysis of 6-paradol, Zingerone and Zerumbone against human estrogen receptor alpha (ERɑ). International Journal of Integrated Engineering, 10 (6 Special Issue 2018: Data Information Engineering) pp. 113-118
2018 Molecular docking and dynamics (MD) simulation of 6-gingerol and 6-shogaol against human estrogen receptor alpha (ERɑ). International Journal of Integrated Engineering, 10 (6 Special Issue 2018: Data Information Engineering) pp. 119-127
2017 In silico binding interactions of dehalogenase (Dehe) with various haloalkanoic acids. Galeri Warisan Sains, 1 (1) pp. 4-6
2017 In silico molecular analysis of novel L-specific dehalogenase from Rhizobium sp. RC1. Malaysian Journal of Microbiology, 13 (1) pp. 50-60
2017 Investigation on plasmid DNA separation under vacuum suction using cellulose generated and polyethersulfone ultra filters. Journal of Applied Pharmaceutical Science, 7 (7) pp. 46-50
2017 Lactic acid bacteria with antimicrobial properties isolated from the instestines Of Japanese Quail (Coturnix coturnix Japonica). Galleri Warisan Sains, 1 (1) pp. 10-12
2015 An S188V mutation alters substrate specificity of non-stereospecific α-haloalkanoic acid dehalogenase E (DehE). PLoS ONE, 10 (3) pp. 1-21
2015 Isolation and identification of 3-chloropropionic acid degrading bacterium from marine spong. Jurnal Teknologi (Sciences & Engineering) , 77 (25) pp. 71-75
2015 Isolation of moderately halophilic lipase producing bacteria from sponges in Pahang coastal water, Malaysia. Jurnal Teknologi, 77 (25) pp. 57-61
2014 Insights into the stereospecificity of the d-specific dehalogenase from Rhizobium sp. RC1 toward D-and L-2-chloropropionate. Biotechnology & Biotechnological Equipment, 28 (4) pp. 608-615
2014 Molecular characterization of monochloroacetate-degrading arthrobacter sp. Strain d2 isolated from Universiti Teknologi Malaysia agricultural area. Bioremediation Journal, 18 (1) pp. 12-19
2013 Identification of functional residues essential for dehalogenation by the non-stereospecific a-haloalkanoic acid dehalogenase from Rhizobium sp. RC1 . Journal of Basic Microbiology, 53 () pp. 1-7
2013 Identification of putative Cof-like hydrolase associated with dehalogenase in Enterobacter cloacae MN1 isolated from the contaminated sea-side area of the Philippines . Malaysian Journal of Microbiology, 9 (3) pp. 253-259
2013 Molecular modelling and functional studies of the non-stereospecific α-haloalkanoic acid dehalogenase (DehE) from Rhizobium sp. RC1 and its association with 3-chloropropionic acid (β-chlorinated aliphatic acid). Biotechnology & Biotechnological Equipment, 27 (2) pp. 3725-3736
Conference or Workshop Item

2023 In silico interaction of nisin-like lactococcus lactis bacteriocin with selected quorum sensing protein members from vibrio sp.. In: 5th International Conference on Biosciences and Medical Engineering (ICBME 2023),
2023 Prospect of antagonising Vibrio disease in shrimp using quorum sensing proteins: I in silico studies base on docking interaction. In: 5th AFOB Malaysia Chapter International Symposium 2023,
2021 Angiotensin-converting enzyme inhibition activity and LCMS analysis of Syzygium polyanthum (Wight) Walp leaves. In: National Symposium on Essential Oils, Plants, Cosmetic and Health,
2021 Characterization of a 2,2-dichloropropionic acid (2,2-dcp) degrading alkalotorelant Bacillus megaterium strain BHS1 isolated from Blue Lake in Turkey. In: International Conference By Biotechnology Society Of Nepal (ICBSN-2021),
2021 In silico development of CRISPR/Cas9 construct for oryza sativa subsp. indica. In: 7th International Conference on Advancement in Science and Technology (iCAST2021).,
2021 In Silico development of CRISPR/Cas9 Construct for Oryza sativa subsp. indica. In: 7th International Conference on Advancement in Science and Technology (iCAST2021).,
2021 Mechanism of angiotensin converting enzyme (ACE) inhibition by Syzygium polyanthum wight (WALP.) leaves. In: IIUM Research Day 2021: An International Online Event for Life Sciences,
2021 Molecular binding interaction of angiotensin converting enzyme and 1-galloyl glucose, the major compound in Syzygium polyanthum leaves. In: 7th International Conference on Advancement in Science and Technology (iCAST2021),
2019 In-silico selection of aptamer: a review on the revolutionary approach to understand the aptamer design and interaction through computational chemistry. In: 2018 International Conference on Chemical Sciences and Engineering: Advance and New Materials (ICCSE 2018),
2019 Molecular docking analysis of β-1,4-Glucosidase from trichoderma harzianum against mycelial cell wall components of macrophomina phaseolina. In: 2nd International Conference on Biosciences and Medical Engineering (ICBME) 2019,
2019 Potential inhibitors of Human Hexokinase II for the development of anti-dengue therapeutics identified via in silico approach. In: Kuliyyah of Engineering Research, Innovation and Commercialization Exhibition 2019 (KERICE 2019),
2019 The mechanistic role of active site residues in non-stereo Haloacid Dehalogenase E (DehE). In: 2nd International Conference on Biosciences & Medical Engineering 2019,
2018 A quest on finding new potential ebola vp40 inhibitors: molecular docking and molecular dynamics simulation studies. In: Computer-aided Drug Design 2018,
2018 Sequence based analysis of fungi associated with decomposition. In: National Seminar on Rural Entrepreneurship Development for Poverty Eradication,
2017 Identifying potential inhibitors of human hexokinase II for the development of anti-dengue therapeutics via virtual screening approaches. In: 4th Asian Regional Conference on Systems Biology,
2017 Molecular docking of selected flavonoid compounds from nelumbo nucifera as potential pancreatic lipase inhibitor. In: 8th Malaysian Symposium of Biomedical Science,
2017 Virulent genes determination of streptococcus agalactiae isolated from Malaysian red tilapia (Oreochromis spp) in Malaysia. In: 10th Symposium on Diseases in Asian Aquaculture (DAA10),
2016 Assessment on the quality on drinking wells exposed to different degrees of submergence during flood in Kelantan. In: Persidangan Kajian Bencana Banjir 2014,
2013 The structural and functional studies of the non-stereospecific α-haloacid dehalogenase (DehE) from rhizobium sp. RC1 . In: Biomicroworld2013,
Book

2017 Microbes in biotechnological applications. Penerbit UTM Press, Universiti Teknologi Malaysia, ISBN: 978-983-52-1442-4
Book Section

2021 In vitro angiotensin-converting enzyme (ACE) inhibition activity of Syzygium polyanthum leaves and its inhibition mechanism. In: Frontiers, ISBN: 978-2-88971-008-9, pp.
2020 Gene expression analysis of fruit bromelain in ripening of Ananas comosus cultivar MD 2. In: Trans Tech Publications Ltd, ISBN: 978-303571664-1, pp. 209-214
2016 Basic analysis of L-specific microbial dehalogenases. In: UTM Press, ISBN: 978-983-52-1271-0, pp. 1-80
2016 Identification of an unknown bacteria and evaluation of its potential use in bioremediation. In: UTM Press, ISBN: 978-983-52-1271-0, pp. 69-80
2016 Taxonomical analysis of of beta-haloalcanoic asid-degrading bacteria. In: Penerbit UTM Press, ISBN: 9789835213465, pp. 20-46
Monograph

2021 Cadangan Pemeliharaan dan Pemuliharaan tasik di kompleks Yayasan Pahang dan kawasan sekitar. In: IIUM Entrepreneurship and Consultancies Sdn Bhd.,
2018 Identification of 3CP-Degrading bacteria from marine sponge and its β-dehalogenase gene. In: ,